Collaborateurs

Thomas Hofstetter

PD Dr. Thomas Hofstetter

Département Chimie de l’environnement

Portrait

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Projets

N-nitrosamines such as N-nitrosodimethylamine (NDMA) are of public and regulatory concern because these potent carcinogens can be formed as unintented by-products during drinking and waste water disinfection/oxidation.
Nitroaromatic explosives persist in the subsurface in different phases (e.g., bound to soil or sediment matrix or as solid-phase residues) and it is extremely challenging to assess biotic and mineral-catalyzed degradation. With the combined analysis of C, N, and H isotope fractionation, we can quantify transformation, even if it takes place via several potentially competing pathways over time-scales of decades.
A new approach for the CSIA of aquatic micropollutants in the sub-microgram/liter range

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Publications sélectionnées

Wijker, R. S.; Pati, S. G.; Zeyer, J.; Hofstetter, T. B. (2015) Enzyme kinetics of different types of flavin-dependent monooxygenases determine the observable contaminant stable isotope fractionation, Environmental Science and Technology Letters, 2(11), 329-334, doi:10.1021/acs.estlett.5b00254, Institutional Repository
Ratti, M.; Canonica, S.; McNeill, K.; Bolotin, J.; Hofstetter, T. B. (2015) Isotope fractionation associated with the indirect photolysis of substituted anilines in aqueous solution, Environmental Science and Technology, 49(21), 12766-12773, doi:10.1021/acs.est.5b03119, Institutional Repository
Ratti, M.; Canonica, S.; McNeill, K.; Bolotin, J.; Hofstetter, T. B. (2015) Isotope fractionation associated with the photochemical dechlorination of chloroanilines, Environmental Science and Technology, 49(16), 9797-9806, doi:10.1021/acs.est.5b02602, Institutional Repository
Ratti, M.; Canonica, S.; McNeill, K.; Erickson, P. R.; Bolotin, J.; Hofstetter, T. B. (2015) Isotope fractionation associated with the direct photolysis of 4-chloroaniline, Environmental Science and Technology, 49(7), 4263-4273, doi:10.1021/es505784a, Institutional Repository
Sander, M.; Hofstetter, T. B.; Gorski, C. A. (2015) Electrochemical analyses of redox-active iron minerals: A review of nonmediated and mediated approaches, Environmental Science and Technology, 49(10), 5862-5878, doi:10.1021/acs.est.5b00006, Institutional Repository
Spahr, S.; Bolotin, J.; Schleucher, J.; Ehlers, I.; von Gunten, U.; Hofstetter, T. B. (2015) Compound-specific carbon, nitrogen, and hydrogen isotope analysis of N-nitrosodimethylamine in aqueous solutions, Analytical Chemistry, 87(5), 2916-2924, doi:10.1021/ac5044169, Institutional Repository
Hofstetter, T. B.; Bolotin, J.; Pati, S. G.; Skarpeli-Liati, M.; Spahr, S.; Wijker, R. S. (2014) Isotope effects as new proxies for organic pollutant transformation, Chimia, 68(11), 788-792, doi:10.2533/chimia.2014.788, Institutional Repository
Gorski, C. A.; Klüpfel, L. E.; Voegelin, A.; Sander, M.; Hofstetter, T. B. (2013) Redox properties of structural Fe in clay minerals: 3. Relationships between smectite redox and structural properties, Environmental Science and Technology, 47(23), 13477-13485, doi:10.1021/es403824x, Institutional Repository
Gorski, C. A.; Klüpfel, L.; Voegelin, A.; Sander, M.; Hofstetter, T. B. (2012) Redox properties of structural Fe in clay minerals. 2. Electrochemical and spectroscopic characterization of electron transfer irreversibility in ferruginous smectite, SWa-1, Environmental Science and Technology, 46(17), 9369-9377, doi:10.1021/es302014u, Institutional Repository
Gorski, C. A.; Aeschbacher, M.; Soltermann, D.; Voegelin, A.; Baeyens, B.; Marques Fernandes, M.; Hofstetter, T. B.; Sander, M. (2012) Redox properties of structural Fe in clay minerals. 1. Electrochemical quantification of electron-donating and -accepting capacities of smectites, Environmental Science and Technology, 46(17), 9360-9368, doi:10.1021/es3020138, Institutional Repository
Schwarzenbach, R. P.; Egli, T.; Hofstetter, T. B.; von Gunten, U.; Wehrli, B. (2010) Global water pollution and human health, Annual Review of Environment and Resources, 35, 109-136, doi:10.1146/annurev-environ-100809-125342, Institutional Repository
Elsner, M.; Jochmann, M. A.; Hofstetter, T. B.; Hunkeler, D.; Bernstein, A.; Schmidt, T. C.; Schimmelmann, A. (2012) Current challenges in compound-specific stable isotope analysis of environmental organic contaminants, Analytical and Bioanalytical Chemistry, 403(9), 2471-2491, doi:10.1007/s00216-011-5683-y, Institutional Repository
Hofstetter, T. B.; Berg, M. (2011) Assessing transformation processes of organic contaminants by compound-specific stable isotope analysis, Trends in Analytical Chemistry, 30(4), 618-627, doi:10.1016/j.trac.2010.10.012, Institutional Repository
Elsner, M.; Hofstetter, T. B. (2011) Current perspectives on the mechanisms of chlorohydrocarbon degradation in subsurface environments: Insight from kinetics, product formation, probe molecules, and isotope fractionation, In: Tratnyek, P. G.; Grundl, T.; Haderlein, S. B. (Eds.), Aquatic Redox Chemistry, 407-439, doi:10.1021/bk-2011-1071.ch019, Institutional Repository
Wijker, R. S.; Bolotin, J.; Nishino, S. F.; Spain, J. C.; Hofstetter, T. B. (2013) Using compound-specific isotope analysis to assess biodegradation of nitroaromatic explosives in the subsurface, Environmental Science and Technology, 47(13), 6872-6883, doi:10.1021/es3051845, Institutional Repository
Pati, S. G.; Kohler, H.-P. E.; Bolotin, J.; Parales, R. E.; Hofstetter, T. B. (2014) Isotope effects of enzymatic dioxygenation of nitrobenzene and 2-nitrotoluene by nitrobenzene dioxygenase, Environmental Science and Technology, 48(18), 10750-10759, doi:10.1021/es5028844, Institutional Repository

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Adresse

E-Mail: thomas.hofstetter@eawag.ch
Téléphone: +41 58 765 5076
Fax: +41 58 765 5802
Adresse: Eawag
Überlandstrasse 133
8600 Dübendorf
Bureau: BU E13

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