Department Environmental Toxicology

How do aquatic organisms respond to stress?

We investigate how freshwater organisms respond to chemical exposure and other stressors in their environment. In particular, we explore adaptive and toxicological response pathways and develop conceptual and computational models to support knowledge-based risk assessment.

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N E W S

July 3, 2019

Swiss 3R Competence Centre (3RCC) to fund six projects worth CHF 1.2 million to advance the replacement, reduction and refinement of animal experiments. Read more

The Scientific Magazine of Swiss Radio SRF1 discusses the rainbow trout gill cell line assay.

Scientific Magazine of Swiss Radio SRF1

The Scientific Magazine of Swiss Radio SRF1 discusses the rainbow trout gill cell line assay.

to the documentary (in German)

Latest publications

Fitzgerald, J. A.; Kirla, K. T.; Zinner, C. P.; vom Berg, C. M. (2019) Emergence of consistent intra-individual locomotor patterns during zebrafish development, Scientific Reports, 9, 13647 (14 pp.), doi:10.1038/s41598-019-49614-y, Institutional Repository
Drieschner, C.; Könemann, S.; Renaud, P.; Schirmer, K. (2019) Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro, Lab on a Chip, 19(19), 3268-3276, doi:10.1039/C9LC00415G, Institutional Repository
Aengenheister, L.; Dugershaw, B. B.; Manser, P.; Wichser, A.; Schoenenberger, R.; Wick, P.; Hesler, M.; Kohl, Y.; Straskraba, S.; Suter, M. J. -F.; Buerki-Thurnherr, T. (2019) Investigating the accumulation and translocation of titanium dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models, European Journal of Pharmaceutics and Biopharmaceutics, 142, 488-497, doi:10.1016/j.ejpb.2019.07.018, Institutional Repository
Schug, H.; Maner, J.; Hülskamp, M.; Begnaud, F.; Debonneville, C.; Berthaud, F.; Gimeno, S.; Schirmer, K. (2019) Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC, ALTEX: Alternatives to Animal Experimentation, (9 pp.), doi:10.14573/altex.1905032, Institutional Repository
Drieschner, C.; Vo, N. T. K.; Schug, H.; Burkard, M.; Bols, N. C.; Renaud, P.; Schirmer, K. (2019) Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF, Cytotechnology, 71(4), 835-848, doi:10.1007/s10616-019-00327-0, Institutional Repository

Awards

Researchers awarded prize for promotion of alternatives to animal experiments

Kristin Schirmer (second from left) and Melanie Fischer (second from right). (Photo: Swiss 3R Competence Centre)

September 4, 2019,
The 3RCC award has been conferred on two Eawag researchers by the 3R Swiss Competence Centre (3RCC) for their outstanding research work. For the first time ever, the researchers managed to obtain ISO certification for a toxicity test using cultured fish gill cells, thanks to their project work in this area. This represents a milestone in the promotion of alternatives to animal experiments. The prize was awarded on September 2nd in Bern.  [read more]

A B C at a glance

José Luis Pérez Pavón (E), Marc Suter (CH), Steffen Pauly (Springer Nature, D), Christian Amatore (F), Wolfram Koch (D), Francesco de Angelis (I), Adam Woolley (USA), Maciej Jarosz (P), Wolfgang Lindner (A), Ulrich Panne (D), Nicola Oberbeckmann-Winter
José Luis Pérez Pavón (E), Marc Suter (CH), Steffen Pauly (Springer Nature, D), Christian Amatore (F), Wolfram Koch (D), Francesco de Angelis (I), Adam Woolley (USA), Maciej Jarosz (P), Wolfgang Lindner (A), Ulrich Panne (D), Nicola Oberbeckmann-Winter (Springer Nature, D)

The co-owners of the journal Analytical and Bioanalytical Chemistry (Springer Nature) met at Eawag, June 28, 2019. The meeting was organized by Marc Suter
Journal strategies were discussed as well as two new editors appointed.