Induction and Spread of Antibiotic Resistances in Livestock

Residues of antibiotics can be found in manure, soil, and water bodies. Within this NRP 49 project we investigated in a first stage the possibilities to assess quantitatively the usage of these compounds in the Swiss agriculture. The main part of the project dealt with the study of the environmental fate of an important class of veterinary antibiotics - the sulfonamides. We studied their sorption, bioavailability and transport behaviour in lab, plot and field experiments and monitoring campaigns in surface and groundwater.

Status

terminated

Contractor

Schweizerischer Nationalfonds, NFP 4

Publications

Burkhardt, M., and Stamm, C. (2007). Depth distribution of sulfonamide antibiotics in pore water of an undisturbed loamy grassland soil. Journal of Environmental Quality 36, 588 - 596.

Burkhardt, M., Stamm, C., Waul, C., Singer, H., and Müller, S. (2005). Surface runoff and transport of sulfonamide antibiotics and tracers on manured grassland. Journal of Environmental Quality 34, 1363 - 1371.

Burkhardt, M., Stoob, K., Stamm, C., Singer, H., and Müller, S. (2004). Veterinary antibiotics in animal slurries - a new environmental issue in grassland research. In "Land use systems in grassland dominated regions" (A. Lüscher, B. Jeangros, W. Kessler, O. Huguenin, M. Lobsiger, N. Millar and D. Suter, eds.), Vol. Vol. 9, pp. 322 - 324. vdf Hochschulverlag, Lucerne.

Kahle, M., and Stamm, C. (2007a). Sorption of the veterinary antibiotic sulfathiazole to organic materials of different origin Environmental Science & Technology 41, 132 -138.

Kahle, M., and Stamm, C. (2007b). Time and pH-dependent sorption of the veterinary antibiotic sulfathiazole to clay minerals and ferrihydrite. Chemosphere 68, 1224 - 1231.

Müller, S., Singer, H., Stoob, K., Burkhardt, M., Hartmann, N., Götz, C., Stamm, C., and Waul, C. (2003). Occurrence and fate of antibiotics in manure, soil and water. Mitteilungen aus Lebensmitteluntersuchung und Hygiene 94, 574 - 578.

Schmitt, H., Martinali, B., Stoob, K., Hamscher, G., van Beelen, P., Smit, E., van Leeuwen, K., and Seinen, W. (2006a). Antibiotika als Umweltkontaminanten - Effekte auf Bodenbakterien. Fortschritte in Ökotoxikologie & Umweltchemie 18, 110 - 118.

Schmitt, H., Stoob, K., Hamscher, G., Smit, E., and Seinen, W. (2006). Tetracyclines and tetracycline reistance in agricultural soils: Microcosm and field studies. Microbial Ecology 51, 267 - 276.

Stoob, K. (2005). Veterinary sulfonamide antibiotics in the environment: Fate in grassland soils and transport to surface waters, ETH Zürich, Zürich.

Stoob, K. (2005). Antibiotikaeinsatz in der Landwirtschaft - Folgen für die Umwelt. EAWAG news 59d, 12 - 15.

Stoob, K., Singer, H., Götz, C., Ruff, M., and Müller, S. R. (2006). Fully automated on-line solid phase extraction coupled directly to LC-MS/MS: Quantification of sulfonamide antibiotics and neutral and acidic herbicides at the low ng/L level in surface waters. Journal of Chromatography A, 1128: 1 - 9.

Stoob, K., Singer, H. P., Mueller, S. R., Schwarzenbach, R., and Stamm, C. (in press). Dissipation and transport of veterinary sulfonamides after manure application to grassland in a small catchment. Environmental Science and Technology.