Staff

Kathrin Fenner

Prof. Dr. Kathrin Fenner

Senior scientist / group leader

Department Environmental Chemistry

About Me

I am passionate about learning how chemicals degrade in the environment and whether any hazardous transformation products are formed during degradation. The ultimate goal of my research is to develop more accurate methods to assess persistence and risk from transformation product formation in regulatory risk assessment procedures. My research focuses on the following three areas in particular.

  1. Prediction of biodegradation pathways and rates
    Current (Q)SBRs tools to predict biodegradation half-lives produce highly uncertain results and available pathway prediction tools suffer from combinatorial explosion due to a lack of methods to prioritize possible pathways. In my research, I mine biotransformation pathway and rate information to develop novel algorithms for biotransformation prediction. In parallel, my team performs bioreactor experiments with pertinent microbial communities and employ high-resolution mass spectrometry to identify transformation products to use that data to further improve biotransformation prediction
  2. Hazard and risk assessment of transformation products
    The goal of this aspect of my research is to develop models and indicators to predict and assess the environmental fate of transformation products. In collaboration with the team of Prof. B. Escher (UFZ Leipzig, Universität Tübingen) we are developing methods to estimate mixture toxicity of transformation products and their parent compound, using the strong structural resemblance to the parent compounds and what is known about parent toxicity as a guiding principle.
  3. Improved tools for persistence assessment
  4. Persistence assessment is key to all chemical legislations in Europe. In my research, I try to contribute to a critical reflection of current persistence assessment paradigms and methods. For instance, I introduced the concept of joint persistence as novel persistence indicator that accounts for transformation product formation. Currently, I am also working on a project that evaluates the value of the OECD 308 guideline for evaluation of persistence of chemicals at the sediment-water interface.

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Projects

Predicting environment-specific biotransformation of chemical contaminants
In regulatory hazard and risk assessment chemical persistence is assessed through a tiered system of degradation studies.

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Curriculum Vitae

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Publications

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Anliker, S., Santiago, S., Fenner, K., & Singer, H. (2022). Large-scale assessment of organic contaminant emissions from chemical and pharmaceutical manufacturing into Swiss surface waters. Water Research, 215, 118221 (10 pp.). doi:10.1016/j.watres.2022.118221, Institutional Repository
Davenport, R., Curtis-Jackson, P., Dalkmann, P., Davies, J., Fenner, K., Hand, L., … Redman, A. (2022). Scientific concepts and methods for moving persistence assessments into the 21st century. Integrated Environmental Assessment and Management. doi:10.1002/ieam.4575, Institutional Repository
Desiante, W. L., Carles, L., Wullschleger, S., Joss, A., Stamm, C., & Fenner, K. (2022). Wastewater microorganisms impact the micropollutant biotransformation potential of natural stream biofilms. Water Research, 217, 118413 (13 pp.). doi:10.1016/j.watres.2022.118413, Institutional Repository
Athanasakoglou, A., & Fenner, K. (2021). Toward characterizing the genetic basis of trace organic contaminant biotransformation in activated sludge: the role of multicopper oxidases as a case study. Environmental Science and Technology, 56(1), 313-324. doi:10.1021/acs.est.1c05803, Institutional Repository
Chalifour, A., Walser, J. C., Pomati, F., & Fenner, K. (2021). Temperature, phytoplankton density and bacteria diversity drive the biotransformation of micropollutants in a lake ecosystem. Water Research, 202, 117412 (10 pp.). doi:10.1016/j.watres.2021.117412, Institutional Repository
Desiante, W. L., Minas, N. S., & Fenner, K. (2021). Micropollutant biotransformation and bioaccumulation in natural stream biofilms. Water Research, 193, 116846 (11 pp.). doi:10.1016/j.watres.2021.116846, Institutional Repository
Fenner, K., & Men, Y. (2021). Comment on "Role of ammonia oxidation in organic micropollutant transformation during wastewater treatment": overlooked evidence to the contrary. Environmental Science and Technology, 55(17), 12128-12129. doi:10.1021/acs.est.1c04178, Institutional Repository
Fenner, K., Elsner, M., Lueders, T., McLachlan, M. S., Wackett, L. P., Zimmermann, M., & Drewes, J. E. (2021). Methodological advances to study contaminant biotransformation: new prospects for understanding and reducing environmental persistence?. ACS ES&T Water, 1(7), 1541-1554. doi:10.1021/acsestwater.1c00025, Institutional Repository
Fenner, K., & Scheringer, M. (2021). The need for chemical simplification as a logical consequence of ever-increasing chemical pollution. Environmental Science and Technology, 55(21), 14470-14472. doi:10.1021/acs.est.1c04903, Institutional Repository
Gallou, F., & Fenner, K. (2021). A roadmap towards sustainable chemical products and processes for Switzerland. Chimia, 75(7), 697-699. doi:10.2533/chimia.2021.697, Institutional Repository
Hübner, U., Wolff, D., Achermann, S., Drewes, J. E., Wick, A., & Fenner, K. (2021). Analyzing (initial) biotransformation reactions as an organizing principle for unraveling the extent of trace organic chemical biotransformation in biofiltration systems. ACS ES&T Water, 1(8), 1921-1931. doi:10.1021/acsestwater.1c00145, Institutional Repository
Kennes-Veiga, D. M., Vogler, B., Fenner, K., Carballa, M., & Lema, J. M. (2021). Heterotrophic enzymatic biotransformations of organic micropollutants in activated sludge. Science of the Total Environment, 780, 146564 (10 pp.). doi:10.1016/j.scitotenv.2021.146564, Institutional Repository
Seller, C., Özel Duygan, B. D., Honti, M., & Fenner, K. (2021). Biotransformation of chemicals at the water–sediment interface - toward a robust simulation study setup. ACS Environmental Au, 1(1), 46-57. doi:10.1021/acsenvironau.1c00006, Institutional Repository
Zumstein, M. T., & Fenner, K. (2021). Towards more sustainable peptide-based antibiotics: stable in human blood, enzymatically hydrolyzed in wastewater?. Chimia, 75(4), 267-271. doi:10.2533/chimia.2021.267, Institutional Repository
Özel Duygan, B. D., Gaille, C., Fenner, K., & van der Meer, J. R. (2021). Assessing antibiotics biodegradation and effects at sub-inhibitory concentrations by quantitative microbial community deconvolution. Frontiers in Environmental Science, 9, 737247 (17 pp.). doi:10.3389/fenvs.2021.737247, Institutional Repository
Achermann, S., Mansfeldt, C. B., Müller, M., Johnson, D. R., & Fenner, K. (2020). Relating metatranscriptomic profiles to the micropollutant biotransformation potential of complex microbial communities. Environmental Science and Technology, 54(1), 235-244. doi:10.1021/acs.est.9b05421, Institutional Repository
Anliker, S., Loos, M., Comte, R., Ruff, M., Fenner, K., & Singer, H. (2020). Assessing emissions from pharmaceutical manufacturing based on temporal high-resolution mass spectrometry data. Environmental Science and Technology, 54(7), 4110-4120. doi:10.1021/acs.est.9b07085, Institutional Repository
Anliker, S., Patrick, M., Fenner, K., & Singer, H. (2020). Quantification of active ingredient losses from formulating pharmaceutical industries and contribution to wastewater treatment plant emissions. Environmental Science and Technology, 54(23), 15046-15056. doi:10.1021/acs.est.0c05178, Institutional Repository
Fenner, K., Screpanti, C., Renold, P., Rouchdi, M., Vogler, B., & Rich, S. (2020). Comparison of small molecule biotransformation half-lives between activated sludge and soil: opportunities for read-across?. Environmental Science and Technology, 54(6), 3148-3158. doi:10.1021/acs.est.9b05104, Institutional Repository
Mansfeldt, C., Deiner, K., Mächler, E., Fenner, K., Eggen, R. I. L., Stamm, C., … Altermatt, F. (2020). Microbial community shifts in streams receiving treated wastewater effluent. Science of the Total Environment, 709, 135727 (12 pp.). doi:10.1016/j.scitotenv.2019.135727, Institutional Repository
Meynet, P., Davenport, R. J., & Fenner, K. (2020). Understanding the dependence of micropollutant biotransformation rates on short-term temperature shifts. Environmental Science and Technology, 54(19), 12214-12225. doi:10.1021/acs.est.0c04017, Institutional Repository
Seller, C., Honti, M., Singer, H., & Fenner, K. (2020). Biotransformation of chemicals in water-sediment suspensions: influencing factors and implications for persistence assessment. Environmental Science and Technology Letters, 7(11), 854-860. doi:10.1021/acs.estlett.0c00725, Institutional Repository
Wang, Y., Fenner, K., & Helbling, D. E. (2020). Clustering micropollutants based on initial biotransformations for improved prediction of micropollutant removal during conventional activated sludge treatment. Environmental Science: Water Research and Technology, 6, 554-565. doi:10.1039/C9EW00838A, Institutional Repository
Mansfeldt, C., Achermann, S., Men, Y., Walser, J. C., Villez, K., Joss, A., … Fenner, K. (2019). Microbial residence time is a controlling parameter of the taxonomic composition and functional profile of microbial communities. ISME Journal, 13(6), 1589-1601. doi:10.1038/s41396-019-0371-6, Institutional Repository
Achermann, S., Bianco, V., Mansfeldt, C. B., Vogler, B., Kolvenbach, B. A., Corvini, P. F. X., & Fenner, K. (2018). Biotransformation of sulfonamide antibiotics in activated sludge: the formation of pterin-conjugates leads to sustained risk. Environmental Science and Technology, 52(11), 6265-6274. doi:10.1021/acs.est.7b06716, Institutional Repository
Achermann, S., Falås, P., Joss, A., Mansfeldt, C., Men, Y., Vogler, B., & Fenner, K. (2018). Trends in micropollutant biotransformation along a solids retention time gradient. Environmental Science and Technology, 52(20), 11601-11611. doi:10.1021/acs.est.8b02763, Institutional Repository
Gulde, R., Anliker, S., Kohler, H. P. E., & Fenner, K. (2018). Ion trapping of amines in protozoa: a novel removal mechanism for micropollutants in activated sludge. Environmental Science and Technology, 52(1), 52-60. doi:10.1021/acs.est.7b03556, Institutional Repository
Honti, M., Bischoff, F., Moser, A., Stamm, C., Baranya, S., & Fenner, K. (2018). Relating degradation of pharmaceutical active ingredients in a stream network to degradation in water-sediment simulation tests. Water Resources Research, 54(11), 9207-9223. doi:10.1029/2018WR023592, Institutional Repository
Wang, Y., Lai, A., Latino, D., Fenner, K., & Helbling, D. E. (2018). Evaluating the environmental parameters that determine aerobic biodegradation half-lives of pesticides in soil with a multivariable approach. Chemosphere, 209, 430-438. doi:10.1016/j.chemosphere.2018.06.077, Institutional Repository
Bianco, V. (2017). Biotransformation of sulfonamide antibiotics in activated sludge: elucidation of main transformation products and their related biotransformation pathways (Master thesis). 140 p. , Institutional Repository
Fenner, K., & Tratnyek, P. G. (2017). QSARs and computational chemistry methods in environmental chemical sciences. Environmental Science: Processes and Impacts, 19(3), 185-187. doi:10.1039/c7em90008b, Institutional Repository
Lai Shuen Lyn, A. (2017). Modelling biodegradation of pesticides using regulatory data (Master thesis). 104 p. , Institutional Repository
Latino, D. A. R. S., Wicker, J., Gütlein, M., Schmid, E., Kramer, S., & Fenner, K. (2017). Eawag-Soil in enviPath: a new resource for exploring regulatory pesticide soil biodegradation pathways and half-life data. Environmental Science: Processes and Impacts, 19(3), 449-464. doi:10.1039/C6EM00697C, Institutional Repository
Lee, M., Blum, L. C., Schmid, E., Fenner, K., & von Gunten, U. (2017). A computer-based prediction platform for the reaction of ozone with organic compounds in aqueous solution: kinetics and mechanisms. Environmental Science: Processes and Impacts, 19(3), 465-476. doi:10.1039/C6EM00584E, Institutional Repository
Men, Y., Achermann, S., Helbling, D. E., Johnson, D. R., & Fenner, K. (2017). Relative contribution of ammonia oxidizing bacteria and other members of nitrifying activated sludge communities to micropollutant biotransformation. Water Research, 109, 217-226. doi:10.1016/j.watres.2016.11.048, Institutional Repository
Riegraf, C., Fenner, K., Werner, I., & Kase, R. (2017). Grenzwerte für Transformationsprodukte. Herleitung von ökotoxikologisch basierten Grenzwerten für TP von Pharmazeutika: eine Fallstudie. Aqua & Gas, 97(2), 46-56. , Institutional Repository
Beretsou, V. G., Psoma, A. K., Gago-Ferrero, P., Aalizadeh, R., Fenner, K., & Thomaidis, N. S. (2016). Identification of biotransformation products of citalopram formed in activated sludge. Water Research, 103, 205-214. doi:10.1016/j.watres.2016.07.029, Institutional Repository
Gulde, R., Meier, U., Schymanski, E. L., Kohler, H. P. E., Helbling, D. E., Derrer, S., … Fenner, K. (2016). Systematic exploration of biotransformation reactions of amine-containing micropollutants in activated sludge. Environmental Science and Technology, 50(6), 2908-2920. doi:10.1021/acs.est.5b05186, Institutional Repository
Honti, M., Hahn, S., Hennecke, D., Junker, T., Shrestha, P., & Fenner, K. (2016). Bridging across OECD 308 and 309 data in search of a robust biotransformation indicator. Environmental Science and Technology, 50(13), 6865-6872. doi:10.1021/acs.est.6b01097, Institutional Repository
Kase, R., & Fenner, K. (2016). Ökotoxikologische Bewertung von Arzneimittel- Transformationsprodukten. Oekotoxzentrum News, 8. , Institutional Repository
Men, Y., Han, P., Helbling, D. E., Jehmlich, N., Herbold, C., Gulde, R., … Fenner, K. (2016). Biotransformation of two pharmaceuticals by the ammonia-oxidizing archaeon Nitrososphaera gargensis. Environmental Science and Technology, 50(9), 4682-4692. doi:10.1021/acs.est.5b06016, Institutional Repository
Shrestha, P., Junker, T., Fenner, K., Hahn, S., Honti, M., Bakkour, R., … Hennecke, D. (2016). Simulation studies to explore biodegradation in water-sediment systems: from OECD 308 to OECD 309. Environmental Science and Technology, 50(13), 6856-6864. doi:10.1021/acs.est.6b01095, Institutional Repository
Singer, H. P., Wössner, A. E., McArdell, C. S., & Fenner, K. (2016). Rapid screening for exposure to "non-target" pharmaceuticals from wastewater effluents by combining HRMS-based suspect screening and exposure modeling. Environmental Science and Technology, 50(13), 6698-6707. doi:10.1021/acs.est.5b03332, Institutional Repository
Wicker, J., Fenner, K., & Kramer, S. (2016). A hybrid machine learning and knowledge based approach to limit combinatorial explosion in biodegradation prediction. In J. Lässig, K. Kersting, & K. Morik (Eds.), Studies in Computational Intelligence: Vol. 645. Computational Sustainability (pp. 75-97). doi:10.1007/978-3-319-31858-5_5, Institutional Repository
Wicker, J., Lorsbach, T., Gütlein, M., Schmid, E., Latino, D., Kramer, S., & Fenner, K. (2016). enviPath – the environmental contaminant biotransformation pathway resource. Nucleic Acids Research, 44(D1), D502-D508. doi:10.1093/nar/gkv1229, Institutional Repository
Gulde, R. K. (2015). Biotransformation of amine-containing micropollutants in activated sludge: pH-dependency and biotransformation reactions (Doctoral dissertation). doi:10.3929/ethz-a-010602038, Institutional Repository
Helbling, D. E., Johnson, D. R., Lee, T. K., Scheidegger, A., & Fenner, K. (2015). A framework for establishing predictive relationships between specific bacterial 16S rRNA sequence abundances and biotransformation rates. Water Research, 70, 471-484. doi:10.1016/j.watres.2014.12.013, Institutional Repository
Honti, M., & Fenner, K. (2015). Deriving persistence indicators from regulatory water-sediment studies - opportunities and limitations in OECD 308 data. Environmental Science and Technology, 49(10), 5879-5886. doi:10.1021/acs.est.5b00788, Institutional Repository
Johnson, D. R., Helbling, D. E., Lee, T. K., Park, J., Fenner, K., Kohler, H. P. E., & Ackermann, M. (2015). Association of biodiversity with the rates of micropollutant biotransformations among full-scale wastewater treatment plant communities. Applied and Environmental Microbiology, 81(2), 666-675. doi:10.1128/AEM.03286-14, Institutional Repository
Johnson, D. R., Helbling, D. E., Men, Y., & Fenner, K. (2015). Can meta-omics help to establish causality between contaminant biotransformations and genes or gene products?. Environmental Science: Water Research and Technology, 1(3), 272-278. doi:10.1039/c5ew00016e, Institutional Repository
Johnson, D. R., Lee, T. K., Park, J., Fenner, K., & Helbling, D. E. (2015). The functional and taxonomic richness of wastewater treatment plant microbial communities are associated with each other and with ambient nitrogen and carbon availability. Environmental Microbiology, 17(12), 4851-4860. doi:10.1111/1462-2920.12429, Institutional Repository
Lee, M., Zimmermann-Steffens, S. G., Arey, J. S., Fenner, K., & von Gunten, U. (2015). Development of prediction models for the reactivity of organic compounds with ozone in aqueous solution by quantum chemical calculations: the role of delocalized and localized molecular orbitals. Environmental Science and Technology, 49(16), 9925-9935. doi:10.1021/acs.est.5b00902, Institutional Repository
Fenner, K., Hofstetter, T., & Canonica, S. (2014). Den Pestiziden auf der Spur. Eawag Newsletter [dtsch. Ausg.] (1), 1-7. Retrieved from http://newsletter.eawag.ch/e/8bbab41cc9ae86ac/nl/webversion/78f27803809d4c4b3a1eee1d/de.html, Institutional Repository
Fenner, K., Hofstetter, T., & Canonica, S. (2014). Tracking the fate of pesticides. Eawag Newsletter [engl. ed.] (1), 1-7. Retrieved from http://newsletter.eawag.ch/e/8bbab41cc9ae86ac/nl/webversion/78f27803809d4c4b3a1eee1d/en.html, Institutional Repository
Gulde, R., Helbling, D. E., Scheidegger, A., & Fenner, K. (2014). pH-dependent biotransformation of ionizable organic micropollutants in activated sludge. Environmental Science and Technology, 48(23), 13760-13768. doi:10.1021/es5037139, Institutional Repository
Hofstetter, T., Fenner, K., & Canonica, S. (2014). Devenir des pesticides dans l’environnement : la traque s’affine. Eawag Newsletter [éd. fr.] (1), 1-7. Retrieved from http://newsletter.eawag.ch/e/8bbab41cc9ae86ac/nl/webversion/78f27803809d4c4b3a1eee1d/fr.html, Institutional Repository
Hollender, J., Bourgin, M., Fenner, K. B., Longrée, P., Mcardell, C. S., Moschet, C., … Singer, H. P. (2014). Exploring the behaviour of emerging contaminants in the water cycle using the capabilities of high resolution mass spectrometry. Chimia, 68(11), 793-798. doi:10.2533/chimia.2014.793, Institutional Repository
Schymanski, E. L., Jeon, J., Gulde, R., Fenner, K., Ruff, M., Singer, H. P., & Hollender, J. (2014). Identifying small molecules via high resolution mass spectrometry: communicating confidence. Environmental Science and Technology, 48(4), 2097-2098. doi:10.1021/es5002105, Institutional Repository
Fenner, K., Canonica, S., Wackett, L. P., & Elsner, M. (2013). Evaluating pesticide degradation in the environment: blind spots and emerging opportunities. Science, 341(6147), 752-758. doi:10.1126/science.1236281, Institutional Repository
Götz, C. W., Fenner, K., & Hollender, J. (2013). Response to comment of Sierra Rayne on "Targeting aquatic microcontaminants for monitoring: Exposure categorization and application to the Swiss situation [Götz et al., Environ Sci Pollut Res (2010) 17:341–354]". Environmental Science and Pollution Research, 20(9), 6678-6680. doi:10.1007/s11356-013-1873-9, Institutional Repository
Helbling, D. E., Johnson, D. R., Honti, M., & Fenner, K. (2012). Micropollutant biotransformation kinetics associate with WWTP process parameters and microbial community characteristics. Environmental Science and Technology, 46(19), 10579-10588. doi:10.1021/es3019012, Institutional Repository
Helbling, D. E., Ackermann, M., Fenner, K., Kohler, H. P. E., & Johnson, D. R. (2012). The activity level of a microbial community function can be predicted from its metatranscriptome. ISME Journal, 6(4), 902-904. doi:10.1038/ismej.2011.158, Institutional Repository
Loos, M., Krauss, M., & Fenner, K. (2012). Pesticide nonextractable residue formation in soil: insights from inverse modeling of degradation time series. Environmental Science and Technology, 46(18), 9830-9837. doi:10.1021/es300505r, Institutional Repository
Escher, B. I., & Fenner, K. (2011). Recent advances in environmental risk assessment of transformation products. Environmental Science and Technology, 45(9), 3835-3847. doi:10.1021/es1030799, Institutional Repository
Fenner, K., Kern, S., Neuwöhner, J., Hollender, J., Singer, H., Schärer, M., … Escher, B. I. (2011). Transformationsprodukte von organischen Mikroverunreinigungen. Untersuchung von Auftreten und Wirkung im Gewässer. GWA Gas, Wasser, Abwasser, 91(5), 335-345. , Institutional Repository
Kern, S., Singer, H., Hollender, J., Schwarzenbach, R. P., & Fenner, K. (2011). Assessing exposure to transformation products of soil-applied organic contaminants in surface water: comparison of model predictions and field data. Environmental Science and Technology, 45(7), 2833-2841. doi:10.1021/es102537b, Institutional Repository
Ng, C. A., Scheringer, M., Fenner, K., & Hungerbühler, K. (2011). A framework for evaluating the contribution of transformation products to chemical persistence in the environment. Environmental Science and Technology, 45(1), 111-117. doi:10.1021/es1010237, Institutional Repository
Alder, A. C., Schaffner, C., Majewsky, M., Klasmeier, J., & Fenner, K. (2010). Fate of β-blocker human pharmaceuticals in surface water: comparison of measured and simulated concentrations in the Glatt Valley Watershed, Switzerland. Water Research, 44(3), 936-948. doi:10.1016/j.watres.2009.10.002, Institutional Repository
Bronner, G., Fenner, K., & Goss, K. U. (2010). Hexadecane/air partitioning coefficients of multifunctional compounds: experimental data and modeling. Fluid Phase Equilibria, 299(2), 207-215. doi:10.1016/j.fluid.2010.09.043, Institutional Repository
Götz, C. W., Stamm, C., Fenner, K., Singer, H., Schärer, M., & Hollender, J. (2010). Targeting aquatic microcontaminants for monitoring: exposure categorization and application to the Swiss situation. Environmental Science and Pollution Research, 17(2), 341-354. doi:10.1007/s11356-009-0167-8, Institutional Repository
Helbling, D. E., Hollender, J., Kohler, H. P. E., Singer, H., & Fenner, K. (2010). High-throughput identification of microbial transformation products of organic micropollutants. Environmental Science and Technology, 44(17), 6621-6627. doi:10.1021/es100970m, Institutional Repository
Helbling, D. E., Hollender, J., Kohler, H. P. E., & Fenner, K. (2010). Structure-based interpretation of biotransformation pathways of amide-containing compounds in sludge-seeded bioreactors. Environmental Science and Technology, 44(17), 6628-6635. doi:10.1021/es101035b, Institutional Repository
Kern, S., Baumgartner, R., Helbling, D. E., Hollender, J., Singer, H., Loos, M. J., … Fenner, K. (2010). A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment. Journal of Environmental Monitoring, 12(11), 2100-2111. doi:10.1039/c0em00238k, Institutional Repository
Kern, S. (2010). Transformation products of organic micropollutants: development and evaluation of methods for assessing their exposure in the aquatic environment (Doctoral dissertation). doi:10.3929/ethz-a-006198560, Institutional Repository
Küster, A., Alder, A. C., Escher, B. I., Duis, K., Fenner, K., Garric, J., … Knacker, T. (2010). Environmental risk assessment of human pharmaceuticals in the European union: a case study with the β-blocker atenolol. Integrated Environmental Assessment and Management, 6(1), 514-523. doi:10.1897/IEAM_2009-050.1, Institutional Repository
Liebig, M., Fernandez, Á. A., Blübaum-Gronau, E., Boxall, A., Brinke, M., Carbonell, G., … Duis, K. (2010). Environmental risk assessment of ivermectin: a case study. Integrated Environmental Assessment and Management, 6(S1), 567-587. doi:10.1002/ieam.96, Institutional Repository
Loos, M. (2010). Modeling of pesticide biodegradation in soil (Master thesis). 87 p. , Institutional Repository
Neuwoehner, J., Zilberman, T., Fenner, K., & Escher, B. I. (2010). QSAR-analysis and mixture toxicity as diagnostic tools: influence of degradation on the toxicity and mode of action of diuron in algae and daphnids. Aquatic Toxicology, 97(1), 58-67. doi:10.1016/j.aquatox.2009.12.005, Institutional Repository
Neuwöhner, J. (2010). Risk assessment and mixture toxicity of organic micropollutants and their transformation products (Doctoral dissertation). doi:10.3929/ethz-a-006188436, Institutional Repository
Oakes, K. D., Coors, A., Escher, B. I., Fenner, K., Garric, J., Gust, M., … Servos, M. R. (2010). Environmental risk assessment for the serotonin re-uptake inhibitor fluoxetine: case study using the european risk assessment framework. Integrated Environmental Assessment and Management, 6(S1), 524-539. doi:10.1002/ieam.77, Institutional Repository
Wicker, J., Fenner, K., Ellis, L., Wackett, L., & Kramer, S. (2010). Predicting biodegradation products and pathways: a hybrid knowledge- and machine learning-based approach. Bioinformatics, 26(6), 814-821. doi:10.1093/bioinformatics/btq024, Institutional Repository
Boethling, R., Fenner, K., Howard, P., Klečka, G., Madsen, T., Snape, J. R., & Whelan, M. J. (2009). Environmental persistence of organic pollutants: guidance for development and review of POP risk profiles. Integrated Environmental Assessment and Management, 5(4), 539-556. doi:10.1897/IEAM_2008-090.1, Institutional Repository
Escher, B. I., Baumgartner, R., Lienert, J., & Fenner, K. (2009). Predicting the ecotoxicological effects of transformation products. In A. B. A. Boxall (Ed.), The handbook of environmental chemistry: Vol. 2. Transformation products of synthetic chemicals in the environment (pp. 205-244). doi:10.1007/698_2_015, Institutional Repository
Fenner, K., Kern, S., Neuwöhner, J., Singer, H., Escher, B., & Hollender, J. (2009). Produits de transformation – un risque pour l’environnement?. Eawag News [éd. fr.], 67, 15-18. , Institutional Repository
Fenner, K., Kern, S., Neuwöhner, J., Singer, H., Escher, B., & Hollender, J. (2009). Transformation products – relevant risk factors?. Eawag News [engl. ed.], 67, 15-18. , Institutional Repository
Fenner, K., Kern, S., Neuwöhner, J., Singer, H., Escher, B., & Hollender, J. (2009). Umwandlungsprodukte – relevante Risikofaktoren?. Eawag News [dtsch. Ausg.], 67, 15-18. , Institutional Repository
Kern, S., Fenner, K., Singer, H. P., Schwarzenbach, R. P., & Hollender, J. (2009). Identification of transformation products of organic contaminants in natural waters by computer-aided prediction and high-resolution mass spectrometry. Environmental Science and Technology, 43(18), 7039-7046. doi:10.1021/es901979h, Institutional Repository
Krogh, K. A., Jensen, G. G., Schneider, M. K., Fenner, K., & Halling-Sørensen, B. (2009). Analysis of the dissipation kinetics of ivermectin at different temperatures and in four different soils. Chemosphere, 75(8), 1097-1104. doi:10.1016/j.chemosphere.2009.01.015, Institutional Repository
Larsbo, M., Lapen, D. R., Topp, E., Metcalfe, C., Abbaspour, K. C., & Fenner, K. (2009). Simulation of pharmaceutical and personal care product transport to tile drains after biosolids application. Journal of Environmental Quality, 38(3), 1274-1285. doi:10.2134/jeq2008.0301, Institutional Repository
Neuwoehner, J., Fenner, K., & Escher, B. I. (2009). Physiological modes of action of fluoxetine and its human metabolites in algae. Environmental Science and Technology, 43(17), 6830-6837. doi:10.1021/es9005493, Institutional Repository
Tülp, H. C., Fenner, K., Schwarzenbach, R. P., & Goss, K. U. (2009). pH-dependent sorption of acidic organic chemicals to soil organic matter. Environmental Science and Technology, 43(24), 9189-9195. doi:10.1021/es902272j, Institutional Repository
Ellis, L. B. M., Gao, J., Fenner, K., & Wackett, L. P. (2008). The University of Minnesota pathway prediction system: predicting metabolic logic. Nucleic Acids Research, 36(S2), W427-W432. doi:10.1093/nar/gkn315, Institutional Repository
Fenner, K., Gao, J., Kramer, S., Ellis, L., & Wackett, L. (2008). Data-driven extraction of relative reasoning rules to limit combinatorial explosion in biodegradation pathway prediction. Bioinformatics, 24(18), 2079-2085. doi:10.1093/bioinformatics/btn378, Institutional Repository
Fenner, K., Schenker, U., & Scheringer, M. (2008). Modelling environmental exposure to transformation products of organic chemicals. In A. B. A. Boxall (Ed.), The handbook of environmental chemistry: Vol. 2. Transformation products of synthetic chemicals in the environment (pp. 121-149). doi:10.1007/698_2_013, Institutional Repository
Huntscha, S., Singer, H., Canonica, S., Schwarzenbach, R. P., & Fenner, K. (2008). Input dynamics and fate in surface water of the herbicide metolachlor and of its highly mobile transformation product metolachlor ESA. Environmental Science and Technology, 42(15), 5507-5513. doi:10.1021/es800395c, Institutional Repository
Larsbo, M., Fenner, K., Stoob, K., Burkhardt, M., Abbaspour, K., & Stamm, C. (2008). Simulating sulfadimidine transport in surface runoff and soil at the microplot and field scale. Journal of Environmental Quality, 37(3), 788-797. doi:10.2134/jeq2007.0432, Institutional Repository
Metcalfe, C. D., Alder, A. C., Halling-Sørensen, B., Krogh, K. A., Fenner, K., Larsbo, M., … Boxall, A. B. A. (2008). Exposure assessment methods for veterinary and human use medicines in the environment: PEC vs MEC comparisons. In K. Kümmerer (Ed.), Pharmaceuticals in the Environment: Sources, Fate, Effects and Risks, (pp. 147-171). Berlin: Springer. , Institutional Repository
Metcalfe, C. D., Boxall, A. B. A., Fenner, K., Kolpin, D., Servos, M., Silberhorn, E., & Staveley, J. (2008). Exposure assessment of veterinary medicines in aquatic systems. In M. Crane, A. B. A. Boxall, & K. Barrett (Eds.), Veterinary medicines in the environment (pp. 57-96). Boca Raton, FL, USA: CRC Press. , Institutional Repository
Stamm, C., Alder, A. C., Fenner, K., Hollender, J., Krauss, M., McArdell, C. S., … Schneider, M. K. (2008). Spatial and temporal patterns of pharmaceuticals in the aquatic environment: a review. Geography Compass, 2(3), 920-955. doi:10.1111/j.1749-8198.2008.00104.x, Institutional Repository
Tülp, H. C., Goss, K. U., Schwarzenbach, R. P., & Fenner, K. (2008). Experimental determination of LSER parameters for a set of 76 diverse pesticides and pharmaceuticals. Environmental Science and Technology, 42(6), 2034-2040. doi:10.1021/es702473f, Institutional Repository
Chèvre, N., Loepfe, C., Fenner, K., Singer, H., & Escher, B. (2007). Pesticides dans les eaux superficielles de Suisse. Critères de qualité basés sur les effets des substances. GWA Gas, Wasser, Abwasser, 87(7), 529-539. , Institutional Repository
Fenner, K., Lanz, V. A., Scheringer, M., & Borsuk, M. E. (2007). Relating atrazine degradation rate in soil to environmental conditions: implications for global fate modeling. Environmental Science and Technology, 41(8), 2840-2846. doi:10.1021/es061923i, Institutional Repository
Gasser, L., Fenner, K., & Scheringer, M. (2007). Indicators for the exposure assessment of transformation products of organic micropollutants. Environmental Science and Technology, 41(7), 2445-2451. doi:10.1021/es062805y, Institutional Repository
Huntscha, S. (2007). Eintrags- und Abbauverhalten von Metolachlor-ESA im Oberflächengewässer. Massenbilanzierung im Greifensee (Master thesis). 60 p. , Institutional Repository
Schneider, M. K., Stamm, C., & Fenner, K. (2007). Selecting scenarios to assess exposure of surface waters to veterinary medicines in Europe. Environmental Science and Technology, 41(13), 4669-4676. doi:10.1021/es062486a, Institutional Repository
Chèvre, N., Loepfe, C., Singer, H., Stamm, C., Fenner, K., & Escher, B. I. (2006). Including mixtures in the determination of water quality criteria for herbicides in surface water. Environmental Science and Technology, 40(2), 426-435. doi:10.1021/es050239l, Institutional Repository
Chèvre, N., Loepfe, C., Fenner, K., Singer, H., Escher, B., & Stamm, C. (2006). Pestizide in Schweizer Oberflächengewässern. Wirkungsbasierte Qualitätskriterien. GWA Gas, Wasser, Abwasser, 86(4), 297-307. , Institutional Repository
Fenner, K., Canonica, S., Escher, B. I., Gasser, L., Spycher, S., & Tülp, H. C. (2006). Developing methods to predict chemical fate and effect endpoints for use within REACH. Chimia, 60(10), 683-690. doi:10.2533/chimia.2006.683, Institutional Repository
Fenner, K., & Escher, B. (2006). Umweltchemie und Ökotoxikologie im Spannungsfeld von Wissenschaft und Praxis. GAIA: Ecological Perspectives for Science and Society, 15(2), 121-126. doi:10.14512/gaia.15.2.11, Institutional Repository
Klasmeier, J., Matthies, M., Macleod, M., Fenner, K., Scheringer, M., Stroebe, M., … Wania, F. (2006). Application of multimedia models for screening assessment of long-range transport potential and overall persistence. Environmental Science and Technology, 40(1), 53-60. doi:10.1021/es0512024, Institutional Repository
Schneider, M. K., Stamm, C., & Fenner, K. (2006). A simple scoring system to identify exposure scenarios for veterinary medicines at the European level. In A. Pistocchi (Ed.), EUR: Vol. 22625 EN. Ecological and human health risk assessment: focussing on complex chemical risk assessment and the identification of highest risk conditions. Proceedings of the 1st open international NoMiracle workshop, Verbania - Intra, Italy June 8-9 2006. Luxembourg: Office for Official Publications of the European Communities. , Institutional Repository
Schwarzenbach, R. P., Escher, B. I., Fenner, K., Hofstetter, T. B., Johnson, C. A., von Gunten, U., & Wehrli, B. (2006). The challenge of micropollutants in aquatic systems. Science, 313(5790), 1072-1077. doi:10.1126/science.1127291, Institutional Repository
Stamm, C., Siber, R., Fenner, K., Singer, H., & Chèvre, N. (2006). Monitoring von Pestizidbelastungen. In Schweizer Oberflächengewässern. GWA Gas, Wasser, Abwasser, 86(8), 629-636. , Institutional Repository
Arp, H. P. H., Fenner, K., & Schmidt, T. C. (2005). Predicting methyl tert-butyl ether, tert-butyl formate, and tert-butyl alcohol levels in the environment using the fugacity approach. Environmental Science and Technology, 39(9), 3237-3244. doi:10.1021/es048711a, Institutional Repository
Fenner, K., Scheringer, M., MacLeod, M., Matthies, M., McKone, T., Stroebe, M., … Wania, F. (2005). Comparing estimates of persistence and long-range transport potential among multimedia models. Environmental Science and Technology, 39(7), 1932-1942. doi:10.1021/es048917b, Institutional Repository
Herensperger, B. (2005). Risikoanalyse von Atrazin und dessen primären Umwandlungsprodukten im Greifenseeeinzugsgebiet (Master thesis). 85 p. , Institutional Repository
Knacker, T., Duis, K., Ternes, T., Fenner, K., Escher, B., Schmitt, H., … Boxall, A. B. A. (2005). The EU-project ERAPharm. Incentives for the further development of guidance documents?. Environmental Science and Pollution Research, 12(2), 62-65. doi:10.1065/espr2005.02.238, Institutional Repository
Boxall, A. B. A., Sinclair, C. J., Fenner, K., Kolpin, D., & Maund, S. J. (2004). When synthetic chemicals degrade in the environment. What are the absolute fate, effects, and potential risks to humans and the ecosystem?. Environmental Science and Technology, 38(19), 368A-375A. doi:10.1021/es040624v, Institutional Repository
Fenner, K., Roth, C., Goss, K. U., & Schwarzenbach, R. P. (2004). Comment on "High-resolution gas chromatography retention data as basis for the estimation of Kow values using PCB congeners as secondary standards". Environmental Science and Technology, 38(7), 2286-2287. doi:10.1021/es035227j, Institutional Repository
Fenner, K., Scheringer, M., & Hungerbühler, K. (2004). Prediction of overall persistence and long-range transport potential with multimedia fate models: robustness and sensitivity of results. Environmental Pollution, 128(1-2), 189-204. doi:10.1016/j.envpol.2003.08.028, Institutional Repository
Scheringer, M., Salzmann, M., Stroebe, M., Wegmann, F., Fenner, K., & Hungerbühler, K. (2004). Long-range transport and global fractionation of POPs: insights from multimedia modeling studies. Environmental Pollution, 128(1-2), 177-188. doi:10.1016/j.envpol.2003.08.027, Institutional Repository
Fenner, K., Scheringer, M., & Hunberbühler, K. (2003). Comment on general fugacity-based model for multiple chemical species. Environmental Toxicology and Chemistry, 22(10), 2219-2220. doi:10.1897/03-138a, Institutional Repository
Fenner, K., Scheringer, M., & Hungerbühler, K. (2003). Joint persistence of transformation products in chemicals assessment: case studies and uncertainty analysis. Risk Analysis, 23(1), 35-53. doi:10.1111/1539-6924.00288, Institutional Repository

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Address

E-Mail: kathrin.fenner@eawag.ch
Phone: +41 58 765 5085
Fax: +41 58 765 5802
Address: Eawag
Überlandstrasse 133
8600 Dübendorf
Office: BU F18

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Expert on

biological degradation, mass spectrometry, micropollutants, organic pollutants

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Research Group

See my team page

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