We recently transferred our knowledge gained for small molecule photochemistry to macromolecular pollutants (> 500 Da), which present an added challenge due to their structurally complexity. In a recent study we focused on antimicrobial peptides (AMPs). AMPs are increasingly important as a last resort against multi-drug resistant bacteria due to resistance formation towards conventional antibiotics. While AMPs have been administered as antibiotics and growth promotors in feedstock since the 1960s and were reconsidered for human medicine by the EMA in 2013, details about their mobility and persistence in the environment remain unknown. Our findings of sorption behaviour, photo- and biotransformation suggest that these processes play a critical role in the fate of the AMPs bacitracins, daptomycin, and polymyxins in environmental systems.
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