Abteilung Umwelttoxikologie

Mechanistische Einblicke in die Toxizität von Reifenpartikeln unter Verwendung von Fischzelllinien


Es hat sich gezeigt, dass Reifen- und Straßenabriebpartikel (TRWP), die durch die Erosion von Reifen während der Fahrt entstehen, einen großen Teil der anthropogenen Partikel ausmachen, die in die Umwelt freigesetzt werden. Dennoch bleibt das potenzielle ökologische Risiko von TRWP und den damit verbundenen Chemikalien für Wasserorganismen weitgehend unerforscht. Unsere Studie zielt darauf ab, die Toxizität zu bestimmen und die Mechanismen zu untersuchen, die durch TRWP und assoziierte Chemikalien bei Fischen unter Verwendung verschiedener Regenbogenforellen-Zelllinien (Oncorhynchus mykiss) induziert werden.

Titelbild: Auto-/Reifenbild, zur Verfügung gestellt vom WBCSD im Rahmen des TIP, Reifenpartikel-Elektronenmikroskopie von unseren EPFL-Partnern, Regenbogenforellenbild erstellt mit BioRender

Publikationen

Extbase Variable Dump
array(2 items)
   publications => '23903' (5 chars)
   libraryUrl => '' (0 chars)
Extbase Variable Dump
array(1 item)
   0 => Snowflake\Publications\Domain\Model\Publicationprototypepersistent entity (uid=23903, pid=124)
      originalId => protected23903 (integer)
      authors => protected'Masset, T.; Ferrari, B. J. D.; Oldham, D.; Dudefoi,
          W.; Minghetti, M.; Schirmer, K.; Bergmann, A.; Vermeirs
         sen, E.; Breider, F.
' (182 chars) title => protected'<em>In vitro</em> digestion of tire particles in a fish model (<em>Oncorhync
         hus mykiss</em>): solubilization kinetics of heavy metals and effects of foo
         d coingestion
' (165 chars) journal => protected'Environmental Science and Technology' (36 chars) year => protected2021 (integer) volume => protected55 (integer) issue => protected'23' (2 chars) startpage => protected'15788' (5 chars) otherpage => protected'15796' (5 chars) categories => protected'tire; tyre; TRWP; heavy metals; microplastics' (45 chars) description => protected'Tire and road wear particles (TRWP) have been shown to represent a large par
         t of anthropogenic particles released into the environment. Nevertheless, th
         e potential ecological risk of TRWP in the different environmental compartme
         nts and their potential toxic impacts on terrestrial and aquatic organisms r
         emain largely underinvestigated. Several heavy metals compose TRWP, includin
         g Zn, which is used as a catalyst during the vulcanization process of rubber
         . This study investigated the solubilization potential of metals from cryoge
         nically milled tire tread (CMTT) and TRWP in simulated gastric fluids (SF<su
         b>GASTRIC</sub>) and simulated intestinal fluids (SF<sub>INTESTINAL</sub>) d
         esigned to mimic rainbow trout (<em>Oncorhynchus mykiss</em>) gastrointestin
         al conditions. Our results indicate that the solubilization of heavy metals
         was greatly enhanced by gastrointestinal fluids compared to that by mineral
         water. After a 26 h <em>in vitro</em> digestion, 9.6 and 23.0% of total Zn c
         ontent of CMTT and TRWP, respectively, were solubilized into the simulated g
         astrointestinal fluids. Coingestion of tire particles (performed with CMTT o
         nly) and surrogate prey items (<em>Gammarus pulex</em>) demonstrated that th
         e animal organic matter reduced the amount of bioavailable Zn solubilized fr
         om CMTT. Contrastingly, in the coingestion scenario with vegetal organic mat
         ter (<em>Lemna minor</em>), high quantities of Zn were solubilized from <em>
         L. minor</em> and cumulated with Zn solubilized from CMTT.
' (1502 chars) serialnumber => protected'0013-936X' (9 chars) doi => protected'10.1021/acs.est.1c04385' (23 chars) uid => protected23903 (integer) _localizedUid => protected23903 (integer)modified _languageUid => protectedNULL _versionedUid => protected23903 (integer)modified pid => protected124 (integer)
Masset, T.; Ferrari, B. J. D.; Oldham, D.; Dudefoi, W.; Minghetti, M.; Schirmer, K.; Bergmann, A.; Vermeirssen, E.; Breider, F. (2021) In vitro digestion of tire particles in a fish model (Oncorhynchus mykiss): solubilization kinetics of heavy metals and effects of food coingestion, Environmental Science and Technology, 55(23), 15788-15796, doi:10.1021/acs.est.1c04385, Institutional Repository

Kontakt

Prof. Dr. Kristin Schirmer Gruppenleiterin und stellv. Abteilungsleiterin Tel. +41 58 765 5266 Inviare e-mail

Team Mitglied

Dr. Anna Toso Postdoktorandin Tel. +41 58 765 6798 Inviare e-mail

In Zusammenarbeit mit

Dr. AlanJames Bergmann Oekotoxzentrum Tel. +41 58 765 6834 Inviare e-mail
Dr. Benoit Ferrari Oekotoxzentrum Tel. +41 58 765 5373 Inviare e-mail

Finanzierung

World Business Council for Sustainable Development’s (WBCSD) Tire Industry Project (TIP)