Mitarbeitende
Elisabeth Janssen
About Me
Umweltchemie von Biomolekülen und Schadstoffen
In meiner Forschung konzentriere ich mich auf chemische Faktoren, die relevant sind um die Wasserqualität zu beurteilen. Diese Information is besonders kritisch da der Eintrag von bioaktiven Chemikalien in unsere Gewässer zunimmt, also Chemikalien die einen Einfluss auf die Gesundheit des Menschen und das Ökosystems haben. Meine Arbeit ist in der Umweltanalytik und Umweltchemie von Enzymen, natürlichen Giftstoffen und Mikroverunreinigungen angesiedelt. Ich untersuche das Umweltverhalten von diesen Stoffen um die mögliche Exposition zu beurteilen und damit zur Risikoabschätzung dieser Chemikalien beizutragen. Die Kernexpertise meiner Arbeitsgruppe liegt in den analytischen Lösungsansätzen, die wir erarbeiten um auch komplexe Biomoleküle und deren Abbauprozesse in der Umwelt zu untersuchen. Mein Ziel ist es zu bestimmen, wie langlebig diese Substanzen in Oberflächengewässern sind, wie sie sich in der Umwelt verhalten, und welche Reaktionsprozesse zu ihrem Abbau führen können. Mein spezieller Fokus hier liegt auf photochemischen und enzymatischen Abbauprozessen.
Gruppenmitglieder:
Senior Scientist
Oliver Brandenberg (2022-present)
PostDoctoral Wissenschaftler/innen:
Dr. Valentin Rougé (2022-present)
Wissenschaftliche Mitarbeiter/in:
Kim Luong (2025-present)
Anita Lopes Souto (2024-present)
Doktoranden/innen:
Xuejian Wang (2022-present)
Juliana Oliveira (2022-present)
Thesis student/in:
Elena Lippuner (2025)
Ehemalige Gruppenmitglieder:
Dr. Francesca Pittino (2022-2023, post doc)
Dr. Martin Jones (2019-2021, post doc)
Dr. Mariana De Almeida Torres (2021/23, visiting PhD from University of São Paulo )
Dr. Antonella Miglione (2023, visiting PhD from University of Naples Federico II)
Dr. Regiane Sanches Natumi (PhD, graduated July 2021)
Dr. Daria Filatova (visiting PhD 2019-2021)
Dr. Christine Egli (PhD, graduated 2019)
Dr. Caroline Davis (PhD, graduated 2019)
Simon Wullschleger (Wissenschaftlicher Mitarbeiter, 2022-2024)
Anne Dax (Wissenschaftliche Mitarbeiterin, 2022-2024)
Projects
Curriculum Vitae
| 2023- | Stv. Abteilungsleiterin in der Umweltchemie, Uchem, Eawag |
| 2022- |
Privatdozentin (PD), ETH, Dept. Umweltsystemwissenschaften Habilitationsschrift: Environmental Chemistry of Biomolecules |
| 2016 - | Gruppenleiterin für Makromolekularer Schadstoffe und Biomoleküle, Abteilung Umweltchemie, Eawag, Dübendorf, Switzerland. |
| 2014 - |
Lektorin an der ETH Zürich |
| 2014-2016 | Oberassistentin, ETH Zürich, Department Umweltchemie, Institute für Biogeochemie und Schadstoffdynamik, Zürich, Schweiz. |
| 2012-2014 | Post-doctoral Researcher, ETH Zürich, Department Umweltchemie mit Prof. Kristopher McNeill. Thema: Photochemie, Zürich, Schweiz. |
| 2011-2012 | Post-doctoral Researcher, Stanford University und naturhistorische Museum, Abteilung Ökotoxikologie, London, UK. |
| 2007-2010 | Doktorand, Stanford University, Department of Civil & Environmental Engineering, betreut von Prof. Richard Luthy. Thema: Sediment Remediation and Toxicokinetics, Stanford, California, USA. |
| 2006-2007 |
M.Sc., Environmental and Engineering Sciences, Stanford University, Department of Civil & Environmental Engineering, Stanford, California, USA |
| 2002-2005 | B.Sc., Water Sciences: Chemistry, Analytics & Microbiology, Universität Duisburg-Essen, Duisburg, Deutschland. |
Veröffentlichungen
Seasonality of cyanobacteria and eukaryotes in Lake Geneva and the impacts of cyanotoxins on growth of the model ciliate Tetrahymena pyriformis. Niveen Ismail, Paul Seguin, Lola Pricam, Elisabeth M.-L. Janssen, Tamar Kohn, Bas W Ibelings, Anna Carratalà. Aquatic Toxicology, Vol. 279, p. 107262 , 2025, https://doi.org/10.1016/j.aquatox.2025.107262. OPEN ACCESS.
Lithic bacterial communities: ecological aspects focusing on Tintenstrich communities. Francesca Pittino, Sabine Fink, Juliana Oliveira, Elisabeth M.-L. Janssen, Scheidegger Christoph. Frontiers in Microbiology, Vol. 15, p. 1-12, 2024, https://doi.org/10.3389/fmicb.2024.1430059, OPEN ACCESS.
UV–vis absorbance spectra, molar extinction coefficients and circular dichroism spectra for the two cyanobacterial metabolites anabaenopeptin A and anabaenopeptin B. Till Steiner, Franziska Schanbacher, Wolfram Lorenzen, Heike Enke, Elisabeth M.-L. Janssen, Timo H.J. Niedermeyer, Karl Gademann. Data in Brief, 57, p.110914, 2024, https://doi.org/10.1016/j.dib.2024.110914, OPEN ACCESS.
Database Version 03 - CyanoMetDB - Comprehensive database of secondary metabolites from cyanobacteria. Elisabeth M.-L. Janssen, Martin R. Jones, Ernani Pinto, Fabiane Dörr, Mariana A. Torres, Fernanda Rios Jacinavicius, Hanna Mazur-Marzec, Karolina Szubert, Robert Konkel, Luciana Tartaglione, Carmela Dell’Aversano, Antonella Miglione, Pearse McCarron, Daniel G. Beach,Christopher O. Miles, David Fewer, Kaarina Sivonen, Jouni Jukela, Matti Wahlsten, Timo H.J. Niedermeyer, Franziska Schanbacher, Pedro Leão, Marco Preto, Paul M. D’Agostino, Martin Baunach, Elke Dittmann, Maria Miguel-Gordo, Raphael Reher, Simon Sieber. Zenodo, S75, 2024, https://zenodo.org/records/13854577, OPEN ACCESS.
Tracking Extensive Portfolio of Cyanotoxins in Five-Year Lake Survey and Identifying Indicator Metabolites of Cyanobacterial Taxa. Xuejian Wang, Simon Wullschleger, Martin Jones, Marta Reyes, Raphael Bossart, Francesco Pomati, Elisabeth M.L. Janssen. Environmental Science and Technology, 57 (37), 16560-16569, 2024, https://doi.org/10.1021/acs.est.4c04813. OPEN ACESSS.
Reactivity of Cyanobacteria Metabolites with Ozone: Multicompound Competition Kinetics. Valentin Rougé, Urs von Gunten, Elisabeth M.L. Janssen. Environmental Science and Technology, 58, 26, 11802–11811, 2024, https://doi.org/10.1021/acs.est.4c02242. OPEN ACESSS.
Lethal and behavioral effects of semi-purified microcystins, Micropeptin and apolar compounds from cyanobacteria on freshwater microcrustacean Thamnocephalus platyurus. Mariana de Almeida Torres, Anne Dax, Ingrid Grand, Colette vom Berg, Ernani Pinto, Elisabeth M.-L Janssen. Aquatic Toxicology, Volume 273, p.106983, 2024, https://doi.org/10.1016/j.aquatox.2024.106983. OPEN ACESSS.
Lethal and sublethal effects towards zebrafish larvae of microcystins and other cyanopeptides produced by cyanobacteria. Mariana de Almeida Torres, Martin R. Jones, Colette vom Berg, Ernani Pinto, Elisabeth M.-L Janssen. Aquatic Toxicology, Volume 263, p.106689, 2023, https://doi.org/10.1016/j.aquatox.2023.106689. OPEN ACESSS.
Do biotransformation data from laboratory experiments reflect micropollutant degradation in a large river basin? Carolin Seller, Laura Varga, Elizabeth Börgardts, Bernadette Vogler, Elisabeth Janssen, Heinz Singer, Kathrin Fenner, Mark Honti, Water Research (235) pp. 119908, 2023 https://doi.org/10.1016/j.watres.2023.119908. OPEN ACESSS.
Cyanobacteria: Extreme Environments and Toxic Metabolites. Francesca Pittino, Juliana Oliveira, Mariana DeAlmeida Torres, Sabine Fink, Elisabeth M.L. Janssen, Christoph Scheidegger, CHIMIA, 76, pp. 967–969, 2022. https://doi.org/10.2533/chimia.2022.967. OPEN ACCESS.
Quantification of multi-class cyanopeptides in Swiss Lakes with automated extraction, enrichment and analysis by online-SPE HPLC-HRMS/MS. Jones M. R. and Janssen E. M.-L., CHIMIA,76, No 1/2, p. 133-144, 2022. https://doi.org/10.2533/chimia.2022.133. OPEN ACCESS.
Cyanobacterial toxins and cyanopeptide transformation kinetics by singlet oxygen and pH-dependence in sunlit surface waters. Natumi R.S., Dieziger Chr., Janssen E.M.-L.* Environmental Science and Technology, 55 (22), pp. 15196–15205, 2021, https://doi.org/10.1021/acs.est.1c04194. OPEN ACCESS.
The Natural Products Atlas 2.0: a database of microbially-derived natural products. van Santen J. A., Poynto E., Iskakova D., McMann E., Alsup T., Clark T., Fergusson C., Fewer D., Hughes, A., McCadden C., Parra Villalobos J., Soldatou S., Rudolf J, Janssen E.M.-L., Duncan K., Linington R.* Nucleic Acid Research, gkab941, 2021. https://doi.org/10.1093/nar/gkab941. OPEN ACCESS.
CyanoMetDB, a comprehensive public database of secondary metabolites from cyanobacteria. Martin Jones, Ernani Pinto, Mariana Torres, Fabiane Dörr, Hanna Mazur-Marzec, Karolina Szubert, Luciana Tartaglione, Carmela Dell'Aversano, Christopher O. Miles, Daniel G. Beach, Pearse McCarron, Kaarina Sivonen, David Fewer, Jouni Jokela, Elisabeth M.-L. Janssen*. Water Research, 197, 117017 2021. https://doi.org/10.1016/j.watres.2021.117017 OPEN ACCESS.
Cyanobacteria and their secondary metabolites in three freshwater reservoirs in the United Kingdom. Daria Filatova, Martin R. Jones, John A. Haley, Oscar Núñez, Marinella Farré, Elisabeth M.-L. Janssen Elisabeth M.-L. Janssen*. Environmental Science Europe 33(29), 2021. https://doi.org/10.1186/s12302-021-00472-4 OPEN ACCESS
Phototransformation kinetics of cyanobacterial toxins and secondary metabolites in surface waters. Regiane Natumi, Sandro Marcotullio, Elisabeth M.-L. Janssen*. Environmental Science Europe 33(26), 2021. https://doi.org/10.1186/s12302-021-00465-3 OPEN ACCESS
Inactivation and Site-specific Oxidation of Aquatic Extracellular Bacterial Leucine Aminopeptidase by Singlet Oxygen. Christine M. Egli, Michael A. Stravs, Elisabeth M.-L. Janssen*. Environmental Science and Technology, 54(22), 14403-14412, 2020. https://doi.org/10.1021/acs.est.0c04696.
Chlorothalonil transformation products in drinking water resources:Wide spread and challenging to abate. Karin Kiefer, Tobias Bader, Nora Minas, Elisabeth Salhi, Elisabeth M.-L. Janssen, Urs Von Gunten, Juliane Hollender*. Water Research, 183, pp. 116066, 2020. https://doi.org/10.1016/j.watres.2020.116066 OPEN ACCESS.
Cyanopeptide co-production dynamics beyond microcystins and effects of growth stages and nutrient availability. Regiane Natumi, Elisabeth M.-L. Janssen*. Environmental Science and Technology, 54(10), pp. 6063–6072, 2020. https://doi.org/10.1021/acs.est.9b07334 OPEN ACCESS.
Inhibition of Extracellular Enzymes Exposed to Cyanopeptides. Christine M. Egli, Regiane Natumi, Martin R. Jones, Elisabeth M.-L. Janssen. CHIMIA, 70(3), pp. 2020. https://doi.org/10.2533/chimia.2020.122. OPEN ACCESS.
Environmental fate processes of antimicrobial peptides daptomycin, bacitracins, and polymyxins. Caroline A. Davis, Elisabeth M.-L. Janssen. Environment International, 134, pp. 105271, 2020. https://doi.org/10.1016/j.envint.2019.105271 OPEN ACCESS.
Cyanobacterial peptides beyond microcystins – A review on co-occurrence, toxicity, and challenges for risk assessment. Elisabeth M.-L. Janssen. Water Research, 151, pp. 488-499, 2019. doi.org/10.1016/j.watres.2018.12.048 OPEN ACCESS.
Non-singlet Oxygen Kinetic Solvent Isotope Effect in Aquatic Photochemistry. Caroline A. Davis, Kristopfer McNeill*, Elisabeth M.-L. Janssen*. Environmental Science and Technology, 17, pp. 9908-9916, 2018.. DOI: 10.1021/acs.est.8b01512 OPEN ACCESS.
Proteomics approach to trace site-specific damage in aquatic extracellular enzymes during photoinactivation. Christine M. Egli, Elisabeth M.-L. Janssen*. Environmental Science and Technology, 52 (14), pp. 7671-7679, 2018. DOI:10.1021/acs.est.7b06439 OPEN ACCESS.
Magnitude and Mechanism of Siderophore-Mediated Competition at Low Iron Solubility in the Pseudomonas aeruginosa Pyochelin System. Konstanze T. Schiessl, Elisabeth Janssen, Stephan M Kraemer, Kristopher McNeill, Martin Ackermann. Frontiers of Microbiology, 8, pp. 1964, 2017. doi: 10.3389/fmicb.2017.01964 OPEN ACCESS.
Environmental Photochemistry of Fenamate NSAIDs and their Radical Intermediates. Caroline A. Davis, Paul R. Erickson, Kristopher McNeill*, Elisabeth M.-L. Janssen*. Environmental Science: Processes and Impacts,, 24;19(5), pp. 656-665, 2017. DOI: 10.1039/C7EM00079K.
Aquatic photochemical kinetics of benzotriazole and structurally related compounds. Elisabeth M.-L. Janssen, Emily Marron, Kristopher McNeill. Environmental Science: Processes and Impacts, 17, pp. 939-946, 2015. DOI: 10.1039/C5EM00045A.
Files
Address
| E-Mail: | elisabeth.janssen@cluttereawag.ch |
| Phone: | +41 58 765 5428 |
| Fax: | +41 58 765 5802 |
| Address: | Eawag
Überlandstrasse 133 8600 Dübendorf |
| Office: | BU F16 |
Forschungsgruppe
Umweltchemie von Biomolekülen und Makromolekularen Schadstoffen
CyanoMetDB - database of secondary metabolites from cyanobacteria
Forschungsschwerpunkt
Biomoleküle, Schadstoffe, natürliche Giftstoffe: Abbau in Gewässern, funktionelle und strukturelle Analytik